Symbol: Name: ID: |
CDH17 cadherin 17, LI cadherin (liver-intestine) GFS:6549 |
Gene name: | CDH17 |
Chromosome: | 8q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HPT-1, cadherin |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1095414 | Rat Genome Database ID: | RGD:619748 |
HGNC ID: | HGNC:1756 | RefSeq IDs: | NM_001144663 |
Entrez Gene ID: | 1015 | Ensembl Gene ID: | ENSG00000079112 |
VEGA IDs: | UniProt ID: | Q12864 | |
UCSC ID: | uc003ygh.2 | OMIM ID: | 603017 |
Pubmed: | PMID9615235 PMID 10191097 | ||
CCDS IDs: | CCDSCCDS6260.1 |
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Products for CDH17 gene
Catalog | Product Name | Application | Company |
GFS:E06549 | cadherin 17, LI cadherin (liver-intestine); ELISA kit | ELISA | n/a |
GFS:A06549 | cadherin 17, LI cadherin (liver-intestine); Anti | ANTIBODIES | n/a |
GFS:P06549 | cadherin 17, LI cadherin (liver-intestine); Protien | Protien | n/a |