Symbol: Name: ID: |
CDH16 cadherin 16, KSP-cadherin GFS:6543 |
Gene name: | CDH16 |
Chromosome: | 16q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106671 | Rat Genome Database ID: | RGD:1311638 |
HGNC ID: | HGNC:1755 | RefSeq IDs: | NM_001204744 |
Entrez Gene ID: | 1014 | Ensembl Gene ID: | ENSG00000166589 |
VEGA IDs: | OTTHUMG00000137518 | UniProt ID: | O75309 |
UCSC ID: | uc002eql.2 | OMIM ID: | 603118 |
Pubmed: | PMID9721215 PMID 7615566 | ||
CCDS IDs: | CCDSCCDS10823.1 |
Cadherin-16 is a protein that in humans is encoded by the CDH16 gene.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH16 gene
Catalog | Product Name | Application | Company |
GFS:E06543 | cadherin 16, KSP-cadherin; ELISA kit | ELISA | n/a |
GFS:A06543 | cadherin 16, KSP-cadherin; Anti | ANTIBODIES | n/a |
GFS:P06543 | cadherin 16, KSP-cadherin; Protien | Protien | n/a |