Symbol: Name: ID: |
CDH15 cadherin 15, type 1, M-cadherin (myotubule) GFS:6540 |
Gene name: | CDH15 |
Chromosome: | 16q24.3 |
Previous Symbols: | CDH3, CDH14 |
Previous Names: | cadherin 15, M-cadherin (myotubule) |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106672 | Rat Genome Database ID: | RGD:1303000 |
HGNC ID: | HGNC:1754 | RefSeq IDs: | NM_004933 |
Entrez Gene ID: | 1013 | Ensembl Gene ID: | ENSG00000129910 |
VEGA IDs: | OTTHUMG00000138045 | UniProt ID: | P55291 |
UCSC ID: | uc002fmt.2 | OMIM ID: | 114019 |
Pubmed: | PMID1427864 | ||
CCDS IDs: | CCDSCCDS10976.1 |
Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Products for CDH15 gene
Catalog | Product Name | Application | Company |
GFS:E06540 | cadherin 15, type 1, M-cadherin (myotubule); ELISA kit | ELISA | n/a |
GFS:A06540 | cadherin 15, type 1, M-cadherin (myotubule); Anti | ANTIBODIES | n/a |
GFS:P06540 | cadherin 15, type 1, M-cadherin (myotubule); Protien | Protien | n/a |