Symbol: Name: ID: |
CDH13 cadherin 13, H-cadherin (heart) GFS:6537 |
Gene name: | CDH13 |
Chromosome: | 16q23.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CDHH |
Name Aliases: | T-cadherin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99551 | Rat Genome Database ID: | RGD:619745 |
HGNC ID: | HGNC:1753 | RefSeq IDs: | NM_001257 |
Entrez Gene ID: | 1012 | Ensembl Gene ID: | ENSG00000140945 |
VEGA IDs: | UniProt ID: | P55290 | |
UCSC ID: | uc002fgx.2 | OMIM ID: | 601364 |
Pubmed: | PMID8673923 PMID 9468307 | ||
CCDS IDs: |
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
Products for CDH13 gene
Catalog | Product Name | Application | Company |
GFS:E06537 | cadherin 13, H-cadherin (heart); ELISA kit | ELISA | n/a |
GFS:A06537 | cadherin 13, H-cadherin (heart); Anti | ANTIBODIES | n/a |
GFS:P06537 | cadherin 13, H-cadherin (heart); Protien | Protien | n/a |