Symbol: Name: ID: |
CDH12 cadherin 12, type 2 (N-cadherin 2) GFS:6530 |
Gene name: | CDH12 |
Chromosome: | 5p14.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Br-cadherin, CDHB |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109503 | Rat Genome Database ID: | RGD:1566350 |
HGNC ID: | HGNC:1751 | RefSeq IDs: | NM_004061 |
Entrez Gene ID: | 1010 | Ensembl Gene ID: | ENSG00000154162 |
VEGA IDs: | OTTHUMG00000090591 | UniProt ID: | P55289 |
UCSC ID: | uc003jgk.2 | OMIM ID: | 600562 |
Pubmed: | PMID7731968 | ||
CCDS IDs: | CCDSCCDS3890.1 |
Cadherin-12 is a protein that in humans is encoded by the CDH12 gene
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH12 gene
Catalog | Product Name | Application | Company |
GFS:E06530 | cadherin 12, type 2 (N-cadherin 2); ELISA kit | ELISA | n/a |
GFS:A06530 | cadherin 12, type 2 (N-cadherin 2); Anti | ANTIBODIES | n/a |
GFS:P06530 | cadherin 12, type 2 (N-cadherin 2); Protien | Protien | n/a |