Symbol: Name: ID: |
ACTN2 actinin, alpha 2 GFS:5515 |
Gene name: | ACTN2 |
Chromosome: | 1q42-q43 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109192 | Rat Genome Database ID: | RGD:1308097 |
HGNC ID: | HGNC:164 | RefSeq IDs: | NM_001103 |
Entrez Gene ID: | Ensembl Gene ID: | ENSG00000077522 | |
VEGA IDs: | OTTHUMG00000040059 | UniProt ID: | P35609 |
UCSC ID: | uc001hyf.2 | OMIM ID: | 102573 |
Pubmed: | PMID1339456 | ||
CCDS IDs: | CCDSCCDS1613.1 |
Actinin, alpha 2, also known as ACTN2, is a protein which in humans is encoded by the ACTN2 gene.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Products for ACTN2 gene
Catalog | Product Name | Application | Company |
GFS:E05515 | actinin, alpha 2; ELISA kit | ELISA | n/a |
GFS:A05515 | actinin, alpha 2; Anti | ANTIBODIES | n/a |
GFS:P05515 | actinin, alpha 2; Protien | Protien | n/a |