Symbol: Name: ID: |
WISP3 WNT1 inducible signaling pathway protein 3 GFS:2532 |
Gene name: | WISP3 |
Chromosome: | 6q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CCN6 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2685581 | Rat Genome Database ID: | RGD:1564120 |
HGNC ID: | HGNC:12771 | RefSeq IDs: | NM_003880 |
Entrez Gene ID: | 8838 | Ensembl Gene ID: | ENSG00000112761 |
VEGA IDs: | OTTHUMG00000015385 | UniProt ID: | O95389 |
UCSC ID: | uc003pvo.2 | OMIM ID: | 603400 |
Pubmed: | PMID9843955 | ||
CCDS IDs: | CCDSCCDS5097.1 CCDS CCDS5098.1 |
WNT1-inducible-signaling pathway protein 3 is a protein that in humans is encoded by the WISP3 gene.
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function: Appears to be required for normal postnatal skeletal growth and cartilage homeostasis.
Products for WISP3 gene
Catalog | Product Name | Application | Company |
GFS:E02532 | WNT1 inducible signaling pathway protein 3; ELISA kit | ELISA | n/a |
GFS:A02532 | WNT1 inducible signaling pathway protein 3; Anti | ANTIBODIES | n/a |
GFS:P02532 | WNT1 inducible signaling pathway protein 3; Protien | Protien | n/a |