Symbol: Name: ID: |
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 GFS:4852 |
Gene name: | B3GNT5 |
Chromosome: | 3q28 |
Previous Symbols: | |
Previous Names: | |
Aliases: | B3GN-T5, beta3Gn-T5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2137302 | Rat Genome Database ID: | RGD:70955 |
HGNC ID: | HGNC:15684 | RefSeq IDs: | NM_032047 |
Entrez Gene ID: | 84002 | Ensembl Gene ID: | ENSG00000176597 |
VEGA IDs: | OTTHUMG00000158436 | UniProt ID: | Q9BYG0 |
UCSC ID: | uc003flk.2 | OMIM ID: | |
Pubmed: | PMID11283017 | ||
CCDS IDs: | CCDSCCDS3244.1 |
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008].
Function: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
Products for B3GNT5 gene
Catalog | Product Name | Application | Company |
GFS:E04852 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; ELISA kit | ELISA | n/a |
GFS:A04852 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; Anti | ANTIBODIES | n/a |
GFS:P04852 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; Protien | Protien | n/a |