| Symbol: Name: ID: |
ARHGAP32 Rho GTPase activating protein 32 GFS:6468 |
| Gene name: | ARHGAP32 |
| Chromosome: | 11q24.3 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | GRIT, KIAA0712, MGC1892, RICS, GC-GAP |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2450166 | Rat Genome Database ID: | RGD:1305267 |
| HGNC ID: | HGNC:17399 | RefSeq IDs: | NM_001142685 |
| Entrez Gene ID: | 9743 | Ensembl Gene ID: | ENSG00000134909 |
| VEGA IDs: | UniProt ID: | A7KAX9 | |
| UCSC ID: | OMIM ID: | 608541 | |
| Pubmed: | PMID12446789 PMID 12819203 PMID 17663722 | ||
| CCDS IDs: | CCDSCCDS31718.1 CCDS CCDS44769.1 | ||
Rho GTPase-activating protein 32 is a protein that in humans is encoded by the RICS gene.
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 (PubMed 12531901)).(supplied by OMIM)
Function: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity).
Products for ARHGAP32 gene
| Catalog | Product Name | Application | Company |
| GFS:E06468 | Rho GTPase activating protein 32; ELISA kit | ELISA | n/a |
| GFS:A06468 | Rho GTPase activating protein 32; Anti | ANTIBODIES | n/a |
| GFS:P06468 | Rho GTPase activating protein 32; Protien | Protien | n/a |
