Symbol: Name: ID: |
ARHGAP12 Rho GTPase activating protein 12 GFS:5469 |
Gene name: | ARHGAP12 |
Chromosome: | 10p11.22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ20737, FLJ10971, FLJ21785 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1922665 | Rat Genome Database ID: | RGD:1310017 |
HGNC ID: | HGNC:16348 | RefSeq IDs: | NM_018287 |
Entrez Gene ID: | 94134 | Ensembl Gene ID: | ENSG00000165322 |
VEGA IDs: | OTTHUMG00000017911 | UniProt ID: | Q8IWW6 |
UCSC ID: | uc001ivz.1 | OMIM ID: | 610577 |
Pubmed: | PMID11854031 | ||
CCDS IDs: | CCDSCCDS7170.1 |
RHO GTPases (see ARHA, MIM 165390) that participate in a wide variety of cellular processes are active in their GTP-bound form and inactive in their GDP-bound form. The hydrolysis of GTP and the inactivation of these GTPases are regulated by GTPase-activating proteins (GAPs), such as ARHGAP12 (Zhang et al., 2002 [PubMed 11854031]).[supplied by OMIM, Mar 2008]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly.
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity).
Products for ARHGAP12 gene
Catalog | Product Name | Application | Company |
GFS:E05469 | Rho GTPase activating protein 12; ELISA kit | ELISA | n/a |
GFS:A05469 | Rho GTPase activating protein 12; Anti | ANTIBODIES | n/a |
GFS:P05469 | Rho GTPase activating protein 12; Protien | Protien | n/a |