Symbol: Name: ID: |
RIN1 Ras and Rab interactor 1 GFS:7584 |
Gene name: | RIN1 |
Chromosome: | 11q13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385695 | Rat Genome Database ID: | RGD:620006 |
HGNC ID: | HGNC:18749 | RefSeq IDs: | NM_004292 |
Entrez Gene ID: | 9610 | Ensembl Gene ID: | ENSG00000174791 |
VEGA IDs: | UniProt ID: | Q13671 | |
UCSC ID: | uc001ohn.1 | OMIM ID: | 605965 |
Pubmed: | PMID9144171 PMID 1849280 | ||
CCDS IDs: | CCDSCCDS31614.1 |
Ras and Rab interactor 1 is a protein that in humans is encoded by the RIN1 gene.
Function: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Products for RIN1 gene
Catalog | Product Name | Application | Company |
GFS:E07584 | Ras and Rab interactor 1; ELISA kit | ELISA | n/a |
GFS:A07584 | Ras and Rab interactor 1; Anti | ANTIBODIES | n/a |
GFS:P07584 | Ras and Rab interactor 1; Protien | Protien | n/a |