Symbol: Name: ID: |
GRINL1A glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A GFS:4150 |
Gene name: | GRINL1A |
Chromosome: | 15q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | complex locus constituent |
Mouse Genome Database ID: | MGI:107282 | Rat Genome Database ID: | RGD:619847 |
HGNC ID: | HGNC:14862 | RefSeq IDs: | NM_001018102 |
Entrez Gene ID: | 81488 | Ensembl Gene ID: | ENSG00000255529 |
VEGA IDs: | OTTHUMG00000138415 | UniProt ID: | P0CAP2 |
UCSC ID: | uc002aev.1 | OMIM ID: | 606485 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS32252.1 CCDS CCDS42045.1 |
GRINL1A complex locus protein 1 is a protein that in humans is encoded by the GRINL1A gene.
This gene (GRINL1A) is part of a complex transcript unit that includes the gene for GRINL1A combined protein (Gcom1). Transcription of this gene occurs at a downstream promoter, with at least three different alternatively spliced variants, grouped together as Gdown for GRINL1A downstream transcripts. The Gcom1 gene uses an upstream promoter for transcription and also has multiple alternatively spliced variants. [provided by RefSeq, Jul 2008].
Function: Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation of transcription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II.
Products for GRINL1A gene
Catalog | Product Name | Application | Company |
GFS:E04150 | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A; ELISA kit | ELISA | n/a |
GFS:A04150 | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A; Anti | ANTIBODIES | n/a |
GFS:P04150 | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A; Protien | Protien | n/a |