Symbol: Name: ID: |
RAD54B RAD54 homolog B (S. cerevisiae) GFS:6314 |
Gene name: | RAD54B |
Chromosome: | 8q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FSBP, RDH54 |
Name Aliases: | fibrinogen silencer binding protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3605986 | Rat Genome Database ID: | RGD:1306507 |
HGNC ID: | HGNC:17228 | RefSeq IDs: | NM_012415 |
Entrez Gene ID: | 25788 | Ensembl Gene ID: | ENSG00000197275 |
VEGA IDs: | OTTHUMG00000133658 | UniProt ID: | Q9Y620 |
UCSC ID: | uc003ygk.2 | OMIM ID: | 604289 |
Pubmed: | PMID10362364 PMID 10851248 | ||
CCDS IDs: | CCDSCCDS6262.1 |
DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008].
Function: Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
Products for RAD54B gene
Catalog | Product Name | Application | Company |
GFS:E06314 | RAD54 homolog B (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06314 | RAD54 homolog B (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06314 | RAD54 homolog B (S. cerevisiae); Protien | Protien | n/a |