| Symbol: Name: ID: |
IKZF4 IKAROS family zinc finger 4 (Eos) GFS:2846 |
| Gene name: | IKZF4 |
| Chromosome: | 12q13 |
| Previous Symbols: | ZNFN1A4 |
| Previous Names: | zinc finger protein, subfamily 1A, 4 (Eos) |
| Aliases: | Eos |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1343139 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:13179 | RefSeq IDs: | NM_022465 |
| Entrez Gene ID: | 64375 | Ensembl Gene ID: | ENSG00000123411 |
| VEGA IDs: | UniProt ID: | Q9H2S9 | |
| UCSC ID: | uc001sjc.1 | OMIM ID: | 606239 |
| Pubmed: | PMID10978333 | ||
| CCDS IDs: | CCDSCCDS44917.1 | ||
Zinc finger protein Eos is a protein that in humans is encoded by the IKZF4 gene.
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM].
Function: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
Products for IKZF4 gene
| Catalog | Product Name | Application | Company |
| GFS:E02846 | IKAROS family zinc finger 4 (Eos); ELISA kit | ELISA | n/a |
| GFS:A02846 | IKAROS family zinc finger 4 (Eos); Anti | ANTIBODIES | n/a |
| GFS:P02846 | IKAROS family zinc finger 4 (Eos); Protien | Protien | n/a |
