Symbol: Name: ID: |
IKZF3 IKAROS family zinc finger 3 (Aiolos) GFS:2845 |
Gene name: | IKZF3 |
Chromosome: | 17q11.2 |
Previous Symbols: | ZNFN1A3 |
Previous Names: | zinc finger protein, subfamily 1A, 3 (Aiolos) |
Aliases: | Aiolos |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1342542 | Rat Genome Database ID: | RGD:1307024 |
HGNC ID: | HGNC:13178 | RefSeq IDs: | NM_012481 |
Entrez Gene ID: | 22806 | Ensembl Gene ID: | ENSG00000161405 |
VEGA IDs: | OTTHUMG00000133250 | UniProt ID: | Q9UKT9 |
UCSC ID: | uc002hsu.2 | OMIM ID: | 606221 |
Pubmed: | PMID9155026 PMID 10552935 | ||
CCDS IDs: | CCDSCCDS11346.1 CCDS CCDS11347.1 CCDS CCDS11348.1 CCDS CCDS11349.1 CCDS CCDS11350.1 CCDS CCDS11351.1 |
Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq].
Function: Transcription factor that plays an important role in the regulation of lymphocyte differentiation.
Products for IKZF3 gene
Catalog | Product Name | Application | Company |
GFS:E02845 | IKAROS family zinc finger 3 (Aiolos); ELISA kit | ELISA | n/a |
GFS:A02845 | IKAROS family zinc finger 3 (Aiolos); Anti | ANTIBODIES | n/a |
GFS:P02845 | IKAROS family zinc finger 3 (Aiolos); Protien | Protien | n/a |