Symbol: Name: ID: |
H2AFY2 H2A histone family, member Y2 GFS:3783 |
Gene name: | H2AFY2 |
Chromosome: | 10q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | macroH2A2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3037658 | Rat Genome Database ID: | RGD:1561371 |
HGNC ID: | HGNC:14453 | RefSeq IDs: | NM_018649 |
Entrez Gene ID: | 55506 | Ensembl Gene ID: | ENSG00000099284 |
VEGA IDs: | OTTHUMG00000018396 | UniProt ID: | Q9P0M6 |
UCSC ID: | uc001jqm.2 | OMIM ID: | |
Pubmed: | PMID11331621 PMID 11262398 | ||
CCDS IDs: | CCDSCCDS7296.1 |
Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene.
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Products for H2AFY2 gene
Catalog | Product Name | Application | Company |
GFS:E03783 | H2A histone family, member Y2; ELISA kit | ELISA | n/a |
GFS:A03783 | H2A histone family, member Y2; Anti | ANTIBODIES | n/a |
GFS:P03783 | H2A histone family, member Y2; Protien | Protien | n/a |