Symbol: Name: ID: |
BHMT2 betaine--homocysteine S-methyltransferase 2 GFS:422 |
Gene name: | BHMT2 |
Chromosome: | 5q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891379 | Rat Genome Database ID: | RGD:1359418 |
HGNC ID: | HGNC:1048 | RefSeq IDs: | NM_001178005 |
Entrez Gene ID: | 23743 | Ensembl Gene ID: | ENSG00000132840 |
VEGA IDs: | OTTHUMG00000108158 | UniProt ID: | Q9H2M3 |
UCSC ID: | uc003kft.2 | OMIM ID: | 605932 |
Pubmed: | PMID11087663 PMID 18230605 | ||
CCDS IDs: | CCDSCCDS4045.1 |
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Products for BHMT2 gene
Catalog | Product Name | Application | Company |
GFS:E00422 | betaine--homocysteine S-methyltransferase 2; ELISA kit | ELISA | n/a |
GFS:A00422 | betaine--homocysteine S-methyltransferase 2; Anti | ANTIBODIES | n/a |
GFS:P00422 | betaine--homocysteine S-methyltransferase 2; Protien | Protien | n/a |