Symbol: Name: ID: |
CD97 CD97 molecule GFS:6204 |
Gene name: | CD97 |
Chromosome: | 19p13 |
Previous Symbols: | |
Previous Names: | CD97 antigen |
Aliases: | TM7LN1 |
Name Aliases: | leukocyte antigen CD97, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1347095 | Rat Genome Database ID: | RGD:1305595 |
HGNC ID: | HGNC:1711 | RefSeq IDs: | NM_001025160 |
Entrez Gene ID: | 976 | Ensembl Gene ID: | ENSG00000123146 |
VEGA IDs: | UniProt ID: | P48960 | |
UCSC ID: | uc002myl.2 | OMIM ID: | 601211 |
Pubmed: | PMID7636245 PMID 8786105 | ||
CCDS IDs: | CCDSCCDS32929.1 CCDS CCDS32930.1 CCDS CCDS32931.1 |
CD97 antigen is a protein that in humans is encoded by the CD97 gene.
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011].
Function: Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
Products for CD97 gene
Catalog | Product Name | Application | Company |
GFS:E06204 | CD97 molecule; ELISA kit | ELISA | n/a |
GFS:A06204 | CD97 molecule; Anti | ANTIBODIES | n/a |
GFS:P06204 | CD97 molecule; Protien | Protien | n/a |