Symbol: Name: ID: |
CD84 CD84 molecule GFS:6133 |
Gene name: | CD84 |
Chromosome: | 1q24 |
Previous Symbols: | |
Previous Names: | CD84 antigen (leukocyte antigen), "CD84 molecule " |
Aliases: | SLAMF5, hCD84, mCD84 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1336885 | Rat Genome Database ID: | RGD:1564553 |
HGNC ID: | HGNC:1704 | RefSeq IDs: | NM_001184879 |
Entrez Gene ID: | 8832 | Ensembl Gene ID: | ENSG00000066294 |
VEGA IDs: | OTTHUMG00000022788 | UniProt ID: | Q9UIB8 |
UCSC ID: | uc001fwf.3 | OMIM ID: | 604513 |
Pubmed: | PMID9310491 | ||
CCDS IDs: | CCDSCCDS1206.1 |
CD84 (Cluster of Differentiation 84) is a human protein encoded by the CD84 gene.
This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011].
Function: Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
Products for CD84 gene
Catalog | Product Name | Application | Company |
GFS:E06133 | CD84 molecule; ELISA kit | ELISA | n/a |
GFS:A06133 | CD84 molecule; Anti | ANTIBODIES | n/a |
GFS:P06133 | CD84 molecule; Protien | Protien | n/a |