Symbol: Name: ID: |
CD79B CD79b molecule, immunoglobulin-associated beta GFS:6079 |
Gene name: | CD79B |
Chromosome: | 17q23 |
Previous Symbols: | IGB |
Previous Names: | CD79B antigen (immunoglobulin-associated beta) |
Aliases: | B29 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:96431 | Rat Genome Database ID: | RGD:620012 |
HGNC ID: | HGNC:1699 | RefSeq IDs: | NM_000626 |
Entrez Gene ID: | 974 | Ensembl Gene ID: | |
VEGA IDs: | UniProt ID: | P40259 | |
UCSC ID: | uc002jdp.1 | OMIM ID: | 147245 |
Pubmed: | PMID9545642 | ||
CCDS IDs: | CCDSCCDS11655.1 CCDS CCDS11656.1 CCDS CCDS42372.1 |
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Products for CD79B gene
Catalog | Product Name | Application | Company |
GFS:E06079 | CD79b molecule, immunoglobulin-associated beta; ELISA kit | ELISA | n/a |
GFS:A06079 | CD79b molecule, immunoglobulin-associated beta; Anti | ANTIBODIES | n/a |
GFS:P06079 | CD79b molecule, immunoglobulin-associated beta; Protien | Protien | n/a |