Symbol: Name: ID: |
CD63 CD63 molecule GFS:6006 |
Gene name: | CD63 |
Chromosome: | 12q12-q13 |
Previous Symbols: | MLA1 |
Previous Names: | CD63 antigen (melanoma 1 antigen) |
Aliases: | ME491, TSPAN30 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99529 | Rat Genome Database ID: | RGD:62080 |
HGNC ID: | HGNC:1692 | RefSeq IDs: | NM_001040034 |
Entrez Gene ID: | 967 | Ensembl Gene ID: | ENSG00000135404 |
VEGA IDs: | UniProt ID: | P08962 | |
UCSC ID: | uc001shn.2 | OMIM ID: | 155740 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS8890.1 CCDS CCDS44915.1 |
CD63 antigen is a protein that in humans is encoded by the CD63 gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Jul 2008].
Function: This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.
Products for CD63 gene
Catalog | Product Name | Application | Company |
GFS:E06006 | CD63 molecule; ELISA kit | ELISA | n/a |
GFS:A06006 | CD63 molecule; Anti | ANTIBODIES | n/a |
GFS:P06006 | CD63 molecule; Protien | Protien | n/a |