Symbol: Name: ID: |
CD58 CD58 molecule GFS:5966 |
Gene name: | CD58 |
Chromosome: | 1p13 |
Previous Symbols: | LFA3 |
Previous Names: | CD58 antigen, (lymphocyte function-associated antigen 3) |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:1688 | RefSeq IDs: | NM_001144822 |
Entrez Gene ID: | 965 | Ensembl Gene ID: | ENSG00000116815 |
VEGA IDs: | OTTHUMG00000022749 | UniProt ID: | P19256 |
UCSC ID: | uc001egm.2 | OMIM ID: | 153420 |
Pubmed: | PMID9510189 | ||
CCDS IDs: | CCDSCCDS888.1 CCDS CCDS44199.1 |
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009].
Function: Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Products for CD58 gene
Catalog | Product Name | Application | Company |
GFS:E05966 | CD58 molecule; ELISA kit | ELISA | n/a |
GFS:A05966 | CD58 molecule; Anti | ANTIBODIES | n/a |
GFS:P05966 | CD58 molecule; Protien | Protien | n/a |