Symbol: Name: ID: |
CD3D CD3d molecule, delta (CD3-TCR complex) GFS:5822 |
Gene name: | CD3D |
Chromosome: | 11q23 |
Previous Symbols: | T3D |
Previous Names: | CD3d antigen, delta polypeptide (TiT3 complex) |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88331 | Rat Genome Database ID: | RGD:2304 |
HGNC ID: | HGNC:1673 | RefSeq IDs: | NM_000732 |
Entrez Gene ID: | 915 | Ensembl Gene ID: | |
VEGA IDs: | UniProt ID: | P04234 | |
UCSC ID: | uc001pss.1 | OMIM ID: | 186790 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS8394.1 CCDS CCDS41724.1 |
T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009].
Function: The CD3 complex mediates signal transduction.
Products for CD3D gene
Catalog | Product Name | Application | Company |
GFS:E05822 | CD3d molecule, delta (CD3-TCR complex); ELISA kit | ELISA | n/a |
GFS:A05822 | CD3d molecule, delta (CD3-TCR complex); Anti | ANTIBODIES | n/a |
GFS:P05822 | CD3d molecule, delta (CD3-TCR complex); Protien | Protien | n/a |