Symbol: Name: ID: |
CD33 CD33 molecule GFS:5695 |
Gene name: | CD33 |
Chromosome: | 19q13.3 |
Previous Symbols: | |
Previous Names: | CD33 antigen (gp67) |
Aliases: | SIGLEC3, SIGLEC-3, p67, FLJ00391 |
Name Aliases: | sialic acid binding Ig-like lectin 3 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99440 | Rat Genome Database ID: | |
HGNC ID: | HGNC:1659 | RefSeq IDs: | NM_001082618 |
Entrez Gene ID: | 945 | Ensembl Gene ID: | ENSG00000105383 |
VEGA IDs: | OTTHUMG00000070561 | UniProt ID: | P20138 |
UCSC ID: | uc002pwa.2 | OMIM ID: | 159590 |
Pubmed: | PMID3139766 PMID 9465907 | ||
CCDS IDs: | CCDSCCDS33084.1 CCDS CCDS46157.1 |
Function: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Products for CD33 gene
Catalog | Product Name | Application | Company |
GFS:E05695 | CD33 molecule; ELISA kit | ELISA | n/a |
GFS:A05695 | CD33 molecule; Anti | ANTIBODIES | n/a |
GFS:P05695 | CD33 molecule; Protien | Protien | n/a |