Symbol: Name: ID: |
CD320 CD320 molecule GFS:5788 |
Gene name: | CD320 |
Chromosome: | 19p13.3-p13.2 |
Previous Symbols: | |
Previous Names: | CD320 antigen |
Aliases: | 8D6, 8D6A |
Name Aliases: | 8D6 antigen |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1860083 | Rat Genome Database ID: | RGD:1305860 |
HGNC ID: | HGNC:16692 | RefSeq IDs: | NM_001165895 |
Entrez Gene ID: | 51293 | Ensembl Gene ID: | ENSG00000167775 |
VEGA IDs: | UniProt ID: | Q9NPF0 | |
UCSC ID: | uc002mjj.1 | OMIM ID: | 606475 |
Pubmed: | PMID10727470 | ||
CCDS IDs: | CCDSCCDS12198.1 |
CD320 (cluster of differentiation 320) is a human gene.
This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011].
Function: Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin.
Products for CD320 gene
Catalog | Product Name | Application | Company |
GFS:E05788 | CD320 molecule; ELISA kit | ELISA | n/a |
GFS:A05788 | CD320 molecule; Anti | ANTIBODIES | n/a |
GFS:P05788 | CD320 molecule; Protien | Protien | n/a |