| Symbol: Name: ID: |
CD274 CD274 molecule GFS:6592 |
| Gene name: | CD274 |
| Chromosome: | 9p24.1 |
| Previous Symbols: | PDCD1LG1 |
| Previous Names: | programmed cell death 1 ligand 1, "CD274 antigen" |
| Aliases: | B7-H, B7H1, PD-L1, PDL1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1926446 | Rat Genome Database ID: | RGD:1566211 |
| HGNC ID: | HGNC:17635 | RefSeq IDs: | NM_014143 |
| Entrez Gene ID: | 29126 | Ensembl Gene ID: | ENSG00000120217 |
| VEGA IDs: | OTTHUMG00000019503 | UniProt ID: | Q9NZQ7 |
| UCSC ID: | uc003zje.2 | OMIM ID: | 605402 |
| Pubmed: | PMID11015443 PMID 10581077 | ||
| CCDS IDs: | CCDSCCDS6464.1 | ||
Programmed cell death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.
Function: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Products for CD274 gene
| Catalog | Product Name | Application | Company |
| GFS:E06592 | CD274 molecule; ELISA kit | ELISA | n/a |
| GFS:A06592 | CD274 molecule; Anti | ANTIBODIES | n/a |
| GFS:P06592 | CD274 molecule; Protien | Protien | n/a |
