Symbol: Name: ID: |
CD1C CD1c molecule GFS:5478 |
Gene name: | CD1C |
Chromosome: | 1q22-q23 |
Previous Symbols: | CD1 |
Previous Names: | CD1C antigen, c polypeptide, "CD1c antigen" |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:1636 | RefSeq IDs: | NM_001765 |
Entrez Gene ID: | 911 | Ensembl Gene ID: | ENSG00000158481 |
VEGA IDs: | OTTHUMG00000017514 | UniProt ID: | P29017 |
UCSC ID: | uc001fru.2 | OMIM ID: | 188340 |
Pubmed: | PMID2447586 | ||
CCDS IDs: | CCDSCCDS1175.1 |
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Products for CD1C gene
Catalog | Product Name | Application | Company |
GFS:E05478 | CD1c molecule; ELISA kit | ELISA | n/a |
GFS:A05478 | CD1c molecule; Anti | ANTIBODIES | n/a |
GFS:P05478 | CD1c molecule; Protien | Protien | n/a |