Symbol: Name: ID: |
CD164 CD164 molecule, sialomucin GFS:5440 |
Gene name: | CD164 |
Chromosome: | 6q21 |
Previous Symbols: | |
Previous Names: | CD164 antigen, sialomucin |
Aliases: | MUC-24, MGC-24 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1859568 | Rat Genome Database ID: | RGD:70942 |
HGNC ID: | HGNC:1632 | RefSeq IDs: | NM_001142401 |
Entrez Gene ID: | 8763 | Ensembl Gene ID: | ENSG00000135535 |
VEGA IDs: | OTTHUMG00000015339 | UniProt ID: | Q04900 |
UCSC ID: | uc003pte.2 | OMIM ID: | 603356 |
Pubmed: | PMID9680353 PMID 9763543 | ||
CCDS IDs: | CCDSCCDS5073.1 CCDS CCDS47462.1 CCDS CCDS47463.1 CCDS CCDS47464.1 CCDS CCDS47465.1 |
Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008].
Function: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity).
Products for CD164 gene
Catalog | Product Name | Application | Company |
GFS:E05440 | CD164 molecule, sialomucin; ELISA kit | ELISA | n/a |
GFS:A05440 | CD164 molecule, sialomucin; Anti | ANTIBODIES | n/a |
GFS:P05440 | CD164 molecule, sialomucin; Protien | Protien | n/a |