Symbol: Name: ID: |
CD14 CD14 molecule GFS:5406 |
Gene name: | CD14 |
Chromosome: | 5q22-q32 |
Previous Symbols: | |
Previous Names: | CD14 antigen |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88318 | Rat Genome Database ID: | RGD:620588 |
HGNC ID: | HGNC:1628 | RefSeq IDs: | NM_000591 |
Entrez Gene ID: | 929 | Ensembl Gene ID: | ENSG00000170458 |
VEGA IDs: | OTTHUMG00000129507 | UniProt ID: | P08571 |
UCSC ID: | uc003lgj.1 | OMIM ID: | 158120 |
Pubmed: | PMID2472171 PMID 2462937 | ||
CCDS IDs: | CCDSCCDS4232.1 |
Cluster of differentiation 14 also known as CD14 is a human gene.
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010].
Function: Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Products for CD14 gene
Catalog | Product Name | Application | Company |
GFS:E05406 | CD14 molecule; ELISA kit | ELISA | n/a |
GFS:A05406 | CD14 molecule; Anti | ANTIBODIES | n/a |
GFS:P05406 | CD14 molecule; Protien | Protien | n/a |