Symbol: Name: ID: |
ACTR3 ARP3 actin-related protein 3 homolog (yeast) GFS:6091 |
Gene name: | ACTR3 |
Chromosome: | 2q14.1 |
Previous Symbols: | |
Previous Names: | ARP3 (actin-related protein 3, yeast) homolog |
Aliases: | ARP3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921367 | Rat Genome Database ID: | RGD:71024 |
HGNC ID: | HGNC:170 | RefSeq IDs: | NM_005721 |
Entrez Gene ID: | 10096 | Ensembl Gene ID: | ENSG00000115091 |
VEGA IDs: | OTTHUMG00000153497 | UniProt ID: | P61158 |
UCSC ID: | uc002tkx.1 | OMIM ID: | 604222 |
Pubmed: | PMID9230079 | ||
CCDS IDs: | CCDSCCDS33277.1 |
Actin-related protein 3 is a protein that in humans is encoded by the ACTR3 gene.
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.
Products for ACTR3 gene
Catalog | Product Name | Application | Company |
GFS:E06091 | ARP3 actin-related protein 3 homolog (yeast); ELISA kit | ELISA | n/a |
GFS:A06091 | ARP3 actin-related protein 3 homolog (yeast); Anti | ANTIBODIES | n/a |
GFS:P06091 | ARP3 actin-related protein 3 homolog (yeast); Protien | Protien | n/a |