Symbol: Name: ID: |
ACTR2 ARP2 actin-related protein 2 homolog (yeast) GFS:5986 |
Gene name: | ACTR2 |
Chromosome: | 2p14 |
Previous Symbols: | |
Previous Names: | ARP2 (actin-related protein 2, yeast) homolog |
Aliases: | ARP2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913963 | Rat Genome Database ID: | RGD:1310826 |
HGNC ID: | HGNC:169 | RefSeq IDs: | NM_001005386 |
Entrez Gene ID: | 10097 | Ensembl Gene ID: | ENSG00000138071 |
VEGA IDs: | OTTHUMG00000129540 | UniProt ID: | P61160 |
UCSC ID: | uc002sdp.2 | OMIM ID: | 604221 |
Pubmed: | PMID9230079 | ||
CCDS IDs: | CCDSCCDS1881.1 CCDS CCDS46307.1 |
Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene.
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
Products for ACTR2 gene
Catalog | Product Name | Application | Company |
GFS:E05986 | ARP2 actin-related protein 2 homolog (yeast); ELISA kit | ELISA | n/a |
GFS:A05986 | ARP2 actin-related protein 2 homolog (yeast); Anti | ANTIBODIES | n/a |
GFS:P05986 | ARP2 actin-related protein 2 homolog (yeast); Protien | Protien | n/a |