Symbol: Name: ID: |
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) GFS:5884 |
Gene name: | ACTR1B |
Chromosome: | 2q11.1-q11.2 |
Previous Symbols: | CTRN2 |
Previous Names: | ARP1 (actin-related protein 1, yeast) homolog B (centractin beta) |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917446 | Rat Genome Database ID: | |
HGNC ID: | HGNC:168 | RefSeq IDs: | NM_005735 |
Entrez Gene ID: | 10120 | Ensembl Gene ID: | ENSG00000115073 |
VEGA IDs: | OTTHUMG00000130549 | UniProt ID: | P42025 |
UCSC ID: | uc002syb.2 | OMIM ID: | 605144 |
Pubmed: | PMID7696711 PMID 10343100 | ||
CCDS IDs: | CCDSCCDS2033.1 |
Beta-centractin is a protein that in humans is encoded by the ACTR1B gene.
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008].
Function: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
Products for ACTR1B gene
Catalog | Product Name | Application | Company |
GFS:E05884 | ARP1 actin-related protein 1 homolog B, centractin beta (yeast); ELISA kit | ELISA | n/a |
GFS:A05884 | ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Anti | ANTIBODIES | n/a |
GFS:P05884 | ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Protien | Protien | n/a |