Symbol: Name: ID: |
ARL2BP ADP-ribosylation factor-like 2 binding protein GFS:6233 |
Gene name: | ARL2BP |
Chromosome: | 16q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | BART1, BART |
Name Aliases: | binder of Arl2 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1349429 | Rat Genome Database ID: | RGD:1561471 |
HGNC ID: | HGNC:17146 | RefSeq IDs: | NM_012106 |
Entrez Gene ID: | 23568 | Ensembl Gene ID: | ENSG00000102931 |
VEGA IDs: | OTTHUMG00000133459 | UniProt ID: | Q9Y2Y0 |
UCSC ID: | uc002elf.1 | OMIM ID: | |
Pubmed: | PMID10488091 PMID 18981177 | ||
CCDS IDs: | CCDSCCDS10776.1 |
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008].
Function: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Products for ARL2BP gene
Catalog | Product Name | Application | Company |
GFS:E06233 | ADP-ribosylation factor-like 2 binding protein; ELISA kit | ELISA | n/a |
GFS:A06233 | ADP-ribosylation factor-like 2 binding protein; Anti | ANTIBODIES | n/a |
GFS:P06233 | ADP-ribosylation factor-like 2 binding protein; Protien | Protien | n/a |