| Symbol: Name: ID: |
NT5M 5',3'-nucleotidase, mitochondrial GFS:4918 |
| Gene name: | NT5M |
| Chromosome: | 17p11.2 |
| Previous Symbols: | |
| Previous Names: | 5' nucleotidase, mitochondrial |
| Aliases: | dNT-2, dNT2, mdN |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1917127 | Rat Genome Database ID: | RGD:1309622 |
| HGNC ID: | HGNC:15769 | RefSeq IDs: | NM_020201 |
| Entrez Gene ID: | 56953 | Ensembl Gene ID: | ENSG00000205309 |
| VEGA IDs: | OTTHUMG00000059277 | UniProt ID: | Q9NPB1 |
| UCSC ID: | uc002grf.2 | OMIM ID: | 605292 |
| Pubmed: | PMID10899995 | ||
| CCDS IDs: | CCDSCCDS32581.1 | ||
This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].
Function: Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Products for NT5M gene
| Catalog | Product Name | Application | Company |
| GFS:E04918 | 5',3'-nucleotidase, mitochondrial; ELISA kit | ELISA | n/a |
| GFS:A04918 | 5',3'-nucleotidase, mitochondrial; Anti | ANTIBODIES | n/a |
| GFS:P04918 | 5',3'-nucleotidase, mitochondrial; Protien | Protien | n/a |
