| Symbol: Name: ID: |
NT5C 5', 3'-nucleotidase, cytosolic GFS:6231 |
| Gene name: | NT5C |
| Chromosome: | 17q25 |
| Previous Symbols: | UMPH2 |
| Previous Names: | 5' nucleotidase, deoxy (pyrimidine), cytosolic type C, "uridine 5-prime monophosphate hydrolase 2" |
| Aliases: | DNT1, DNT-1, PN-I, cdN, dNT-1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1354954 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:17144 | RefSeq IDs: | NM_014595 |
| Entrez Gene ID: | 30833 | Ensembl Gene ID: | ENSG00000125458 |
| VEGA IDs: | UniProt ID: | Q8TCD5 | |
| UCSC ID: | uc002jmx.2 | OMIM ID: | 191720 |
| Pubmed: | PMID10899995 | ||
| CCDS IDs: | CCDSCCDS11715.1 | ||
5'(3')-deoxyribonucleotidase, cytosolic type is an enzyme that in humans is encoded by the NT5C gene.
Pyrimidine 5-prime nucleotidase (P5N; EC 3.1.3.5), also called uridine 5-prime monophosphate hydrolase (UMPH), catalyzes the dephosphorylation of the pyrimidine 5-prime monophosphates UMP and CMP to the corresponding nucleosides. There are 2 isozymes of pyrimidine 5-prime nucleotidase in red blood cells, referred to as type I (UMPH1; MIM 606224) and type II (UMPH2).[supplied by OMIM, Jul 2002]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Products for NT5C gene
| Catalog | Product Name | Application | Company |
| GFS:E06231 | 5', 3'-nucleotidase, cytosolic; ELISA kit | ELISA | n/a |
| GFS:A06231 | 5', 3'-nucleotidase, cytosolic; Anti | ANTIBODIES | n/a |
| GFS:P06231 | 5', 3'-nucleotidase, cytosolic; Protien | Protien | n/a |
