Symbol: Name: ID: |
XYLT1 xylosyltransferase I GFS:4722 |
Gene name: | XYLT1 |
Chromosome: | 16p12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | XT-I, PXYLT1 |
Name Aliases: | protein xylosyltransferase 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2451073 | Rat Genome Database ID: | RGD:620093 |
HGNC ID: | HGNC:15516 | RefSeq IDs: | NM_022166 |
Entrez Gene ID: | 64131 | Ensembl Gene ID: | ENSG00000103489 |
VEGA IDs: | OTTHUMG00000129975 | UniProt ID: | Q86Y38 |
UCSC ID: | uc002dfa.2 | OMIM ID: | 608124 |
Pubmed: | PMID11099377 | ||
CCDS IDs: | CCDSCCDS10569.1 |
Xylosyltransferase 1 is an enzyme that in humans is encoded by the XYLT1 gene.
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
Products for XYLT1 gene
Catalog | Product Name | Application | Company |
GFS:E04722 | xylosyltransferase I; ELISA kit | ELISA | n/a |
GFS:A04722 | xylosyltransferase I; Anti | ANTIBODIES | n/a |
GFS:P04722 | xylosyltransferase I; Protien | Protien | n/a |