Symbol: Name: ID: |
VAMP7 vesicle-associated membrane protein 7 GFS:1348 |
Gene name: | VAMP7 |
Chromosome: | Xq28 and Yq12 |
Previous Symbols: | SYBL1 |
Previous Names: | synaptobrevin-like 1 |
Aliases: | VAMP-7, TI-VAMP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1096399 | Rat Genome Database ID: | RGD:621558 |
HGNC ID: | HGNC:11486 | RefSeq IDs: | NM_001145149 |
Entrez Gene ID: | 6845 | Ensembl Gene ID: | ENSG00000124333 |
VEGA IDs: | OTTHUMG00000022679 | UniProt ID: | P51809 |
UCSC ID: | uc004fnr.2 | OMIM ID: | 300053 |
Pubmed: | PMID8640232 PMID 11440841 | ||
CCDS IDs: | CCDSCCDS14770.4 CCDS CCDS48199.1 |
Vesicle-associated membrane protein 7 (VAMP-7) is a protein that in humans is encoded by the VAMP7 gene. This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
Products for VAMP7 gene
Catalog | Product Name | Application | Company |
GFS:E01348 | vesicle-associated membrane protein 7; ELISA kit | ELISA | n/a |
GFS:A01348 | vesicle-associated membrane protein 7; Anti | ANTIBODIES | n/a |
GFS:P01348 | vesicle-associated membrane protein 7; Protien | Protien | n/a |