Symbol: Name: ID: |
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) GFS:2423 |
Gene name: | VAMP2 |
Chromosome: | 17pter-p12 |
Previous Symbols: | SYB2 |
Previous Names: | |
Aliases: | VAMP-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1313277 | Rat Genome Database ID: | RGD:3949 |
HGNC ID: | HGNC:12643 | RefSeq IDs: | NM_014232 |
Entrez Gene ID: | 6844 | Ensembl Gene ID: | ENSG00000220205 |
VEGA IDs: | OTTHUMG00000150254 | UniProt ID: | P63027 |
UCSC ID: | uc010cnt.1 | OMIM ID: | 185881 |
Pubmed: | PMID1976629 | ||
CCDS IDs: | CCDSCCDS32561.1 |
Vesicle-associated membrane protein 2 is a protein that in humans is encoded by the VAMP2 gene.
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Products for VAMP2 gene
Catalog | Product Name | Application | Company |
GFS:E02423 | vesicle-associated membrane protein 2 (synaptobrevin 2); ELISA kit | ELISA | n/a |
GFS:A02423 | vesicle-associated membrane protein 2 (synaptobrevin 2); Anti | ANTIBODIES | n/a |
GFS:P02423 | vesicle-associated membrane protein 2 (synaptobrevin 2); Protien | Protien | n/a |