Symbol: Name: ID: |
UPK3A uroplakin 3A GFS:2365 |
Gene name: | UPK3A |
Chromosome: | 22q13.31 |
Previous Symbols: | UPK3 |
Previous Names: | uroplakin 3 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98914 | Rat Genome Database ID: | RGD:1310633 |
HGNC ID: | HGNC:12580 | RefSeq IDs: | NM_001167574 |
Entrez Gene ID: | 7380 | Ensembl Gene ID: | ENSG00000100373 |
VEGA IDs: | OTTHUMG00000151339 | UniProt ID: | O75631 |
UCSC ID: | uc003bfy.2 | OMIM ID: | 611559 |
Pubmed: | PMID9818021 | ||
CCDS IDs: | CCDSCCDS14064.1 |
Uroplakin-3a is a protein that in humans is encoded by the UPK3A gene.
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.
Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Products for UPK3A gene
Catalog | Product Name | Application | Company |
GFS:E02365 | uroplakin 3A; ELISA kit | ELISA | n/a |
GFS:A02365 | uroplakin 3A; Anti | ANTIBODIES | n/a |
GFS:P02365 | uroplakin 3A; Protien | Protien | n/a |