Symbol: Name: ID: |
UPK1B uroplakin 1B GFS:2362 |
Gene name: | UPK1B |
Chromosome: | 3q13.32 |
Previous Symbols: | UPK1 |
Previous Names: | |
Aliases: | TSPAN20 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98912 | Rat Genome Database ID: | RGD:1307806 |
HGNC ID: | HGNC:12578 | RefSeq IDs: | NM_006952 |
Entrez Gene ID: | 7348 | Ensembl Gene ID: | ENSG00000114638 |
VEGA IDs: | OTTHUMG00000159354 | UniProt ID: | O75841 |
UCSC ID: | uc003ecc.2 | OMIM ID: | 602380 |
Pubmed: | PMID9935153 PMID 9846985 | ||
CCDS IDs: | CCDSCCDS2985.1 |
Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity),
Products for UPK1B gene
Catalog | Product Name | Application | Company |
GFS:E02362 | uroplakin 1B; ELISA kit | ELISA | n/a |
GFS:A02362 | uroplakin 1B; Anti | ANTIBODIES | n/a |
GFS:P02362 | uroplakin 1B; Protien | Protien | n/a |