Symbol: Name: ID: |
UHRF2 ubiquitin-like with PHD and ring finger domains 2 GFS:2346 |
Gene name: | UHRF2 |
Chromosome: | 9p24.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RNF107, NIRF, URF2, MGC33463 |
Name Aliases: | Np95-like ring finger protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923718 | Rat Genome Database ID: | RGD:1309990 |
HGNC ID: | HGNC:12557 | RefSeq IDs: | NM_152896 |
Entrez Gene ID: | 115426 | Ensembl Gene ID: | ENSG00000147854 |
VEGA IDs: | OTTHUMG00000019521 | UniProt ID: | Q96PU4 |
UCSC ID: | uc003zjy.2 | OMIM ID: | |
Pubmed: | PMID12176013 | ||
CCDS IDs: | CCDSCCDS6469.1 |
E3 ubiquitin-protein ligase UHRF2 is an enzyme that in humans is encoded by the UHRF2 gene.
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. [provided by RefSeq].
Function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. May participate in methylation-dependent transcriptional regulation. Important for G1/S transition. Overexpression causes G1 phase cell arrest.
Products for UHRF2 gene
Catalog | Product Name | Application | Company |
GFS:E02346 | ubiquitin-like with PHD and ring finger domains 2; ELISA kit | ELISA | n/a |
GFS:A02346 | ubiquitin-like with PHD and ring finger domains 2; Anti | ANTIBODIES | n/a |
GFS:P02346 | ubiquitin-like with PHD and ring finger domains 2; Protien | Protien | n/a |