Symbol: Name: ID: |
TUBB2A tubulin, beta 2A GFS:2214 |
Gene name: | TUBB2A |
Chromosome: | 6p25.2 |
Previous Symbols: | TUBB, TUBB2 |
Previous Names: | tubulin, beta polypeptide, "tubulin, beta 2" |
Aliases: | dJ40E16.7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107861 | Rat Genome Database ID: | RGD:1588452 |
HGNC ID: | HGNC:12412 | RefSeq IDs: | NM_001069 |
Entrez Gene ID: | 7280 | Ensembl Gene ID: | ENSG00000137267 |
VEGA IDs: | UniProt ID: | Q13885 | |
UCSC ID: | uc003mvc.2 | OMIM ID: | |
Pubmed: | PMID14574404 | ||
CCDS IDs: | CCDSCCDS4484.1 |
Tubulin beta-2A chain is a protein that in humans is encoded by the TUBB2A gene. Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the spindle fibers for separating chromosomes during mitosis.
Products for TUBB2A gene
Catalog | Product Name | Application | Company |
GFS:E02214 | tubulin, beta 2A; ELISA kit | ELISA | n/a |
GFS:A02214 | tubulin, beta 2A; Anti | ANTIBODIES | n/a |
GFS:P02214 | tubulin, beta 2A; Protien | Protien | n/a |