Symbol: Name: ID: |
TUBB1 tubulin, beta 1 GFS:5385 |
Gene name: | TUBB1 |
Chromosome: | 20q13.32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | dJ543J19.4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107814 | Rat Genome Database ID: | |
HGNC ID: | HGNC:16257 | RefSeq IDs: | NM_030773 |
Entrez Gene ID: | 81027 | Ensembl Gene ID: | ENSG00000101162 |
VEGA IDs: | OTTHUMG00000032860 | UniProt ID: | Q9H4B7 |
UCSC ID: | uc002yak.2 | OMIM ID: | 612901 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS13475.1 |
Tubulin beta-1 chain is a protein that in humans is encoded by the TUBB1 gene.
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
Products for TUBB1 gene
Catalog | Product Name | Application | Company |
GFS:E05385 | tubulin, beta 1; ELISA kit | ELISA | n/a |
GFS:A05385 | tubulin, beta 1; Anti | ANTIBODIES | n/a |
GFS:P05385 | tubulin, beta 1; Protien | Protien | n/a |