Symbol: Name: ID: |
TMOD2 tropomodulin 2 (neuronal) GFS:1688 |
Gene name: | TMOD2 |
Chromosome: | 15q21.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NTMOD |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1355335 | Rat Genome Database ID: | RGD:61948 |
HGNC ID: | HGNC:11872 | RefSeq IDs: | NM_001142885 |
Entrez Gene ID: | 29767 | Ensembl Gene ID: | ENSG00000128872 |
VEGA IDs: | OTTHUMG00000131805 | UniProt ID: | Q9NZR1 |
UCSC ID: | uc002abk.2 | OMIM ID: | 602928 |
Pubmed: | PMID10662549 | ||
CCDS IDs: | CCDSCCDS10144.1 CCDS CCDS45260.1 |
The TMOD2 gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Products for TMOD2 gene
Catalog | Product Name | Application | Company |
GFS:E01688 | tropomodulin 2 (neuronal); ELISA kit | ELISA | n/a |
GFS:A01688 | tropomodulin 2 (neuronal); Anti | ANTIBODIES | n/a |
GFS:P01688 | tropomodulin 2 (neuronal); Protien | Protien | n/a |