Symbol: Name: ID: |
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) GFS:1631 |
Gene name: | TIMM13 |
Chromosome: | 19p13.3 |
Previous Symbols: | TIMM13B |
Previous Names: | translocase of inner mitochondrial membrane 13 (yeast) homolog B |
Aliases: | Tim13 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1353432 | Rat Genome Database ID: | RGD:628845 |
HGNC ID: | HGNC:11816 | RefSeq IDs: | NM_012458 |
Entrez Gene ID: | 26517 | Ensembl Gene ID: | ENSG00000099800 |
VEGA IDs: | UniProt ID: | Q9Y5L4 | |
UCSC ID: | uc002lvx.1 | OMIM ID: | 607383 |
Pubmed: | PMID10552927 PMID 17329230 | ||
CCDS IDs: | CCDSCCDS12089.1 |
Mitochondrial import inner membrane translocase subunit Tim13 is an enzyme that in humans is encoded by the TIMM13 gene. This gene encodes a translocase with similarity to yeast mitochondrial proteins that are involved in the import of metabolite transporters from the cytoplasm and into the mitochondrial inner membrane. The encoded protein and the TIMM8a protein form a 70 kDa complex in the intermembrane space. This gene is in a head-to-tail orientation with the gene for lamin B2. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Products for TIMM13 gene
Catalog | Product Name | Application | Company |
GFS:E01631 | translocase of inner mitochondrial membrane 13 homolog (yeast); ELISA kit | ELISA | n/a |
GFS:A01631 | translocase of inner mitochondrial membrane 13 homolog (yeast); Anti | ANTIBODIES | n/a |
GFS:P01631 | translocase of inner mitochondrial membrane 13 homolog (yeast); Protien | Protien | n/a |