Symbol: Name: ID: |
TBL1Y transducin (beta)-like 1, Y-linked GFS:7350 |
Gene name: | TBL1Y |
Chromosome: | Yp11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | TBL1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18502 | RefSeq IDs: | NM_033284 |
Entrez Gene ID: | 90665 | Ensembl Gene ID: | ENSG00000092377 |
VEGA IDs: | OTTHUMG00000035299 | UniProt ID: | Q9BQ87 |
UCSC ID: | uc004frd.2 | OMIM ID: | 400033 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS14779.1 |
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Function: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity).
Products for TBL1Y gene
Catalog | Product Name | Application | Company |
GFS:E07350 | transducin (beta)-like 1, Y-linked; ELISA kit | ELISA | n/a |
GFS:A07350 | transducin (beta)-like 1, Y-linked; Anti | ANTIBODIES | n/a |
GFS:P07350 | transducin (beta)-like 1, Y-linked; Protien | Protien | n/a |