Symbol: Name: ID: |
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) GFS:1568 |
Gene name: | TFDP2 |
Chromosome: | 3q23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Dp-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107167 | Rat Genome Database ID: | RGD:1305814 |
HGNC ID: | HGNC:11751 | RefSeq IDs: | NM_001178138 |
Entrez Gene ID: | 7029 | Ensembl Gene ID: | ENSG00000114126 |
VEGA IDs: | OTTHUMG00000159101 | UniProt ID: | Q14188 |
UCSC ID: | uc010hur.2 | OMIM ID: | 602160 |
Pubmed: | PMID7784053 PMID 9027491 | ||
CCDS IDs: | CCDSCCDS43159.1 |
Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene. The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Products for TFDP2 gene
Catalog | Product Name | Application | Company |
GFS:E01568 | transcription factor Dp-2 (E2F dimerization partner 2); ELISA kit | ELISA | n/a |
GFS:A01568 | transcription factor Dp-2 (E2F dimerization partner 2); Anti | ANTIBODIES | n/a |
GFS:P01568 | transcription factor Dp-2 (E2F dimerization partner 2); Protien | Protien | n/a |