Symbol: Name: ID: |
TFDP1 transcription factor Dp-1 GFS:1566 |
Gene name: | TFDP1 |
Chromosome: | 13q34 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Dp-1, DRTF1, DP1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:101934 | Rat Genome Database ID: | |
HGNC ID: | HGNC:11749 | RefSeq IDs: | NM_007111 |
Entrez Gene ID: | 7027 | Ensembl Gene ID: | ENSG00000198176 |
VEGA IDs: | OTTHUMG00000017388 | UniProt ID: | Q14186 |
UCSC ID: | uc001vtw.2 | OMIM ID: | 189902 |
Pubmed: | PMID8413592 PMID 9027491 | ||
CCDS IDs: | CCDSCCDS9538.1 |
Transcription factor Dp-1 is a protein that in humans is encoded by the TFDP1 gene. This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Products for TFDP1 gene
Catalog | Product Name | Application | Company |
GFS:E01566 | transcription factor Dp-1; ELISA kit | ELISA | n/a |
GFS:A01566 | transcription factor Dp-1; Anti | ANTIBODIES | n/a |
GFS:P01566 | transcription factor Dp-1; Protien | Protien | n/a |