Symbol: Name: ID: |
TES testis derived transcript (3 LIM domains) GFS:3915 |
Gene name: | TES |
Chromosome: | 7q31.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DKFZP586B2022, TESS-2, TESTIN |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:105081 | Rat Genome Database ID: | RGD:1566346 |
HGNC ID: | HGNC:14620 | RefSeq IDs: | NM_015641 |
Entrez Gene ID: | 26136 | Ensembl Gene ID: | ENSG00000135269 |
VEGA IDs: | OTTHUMG00000023092 | UniProt ID: | Q9UGI8 |
UCSC ID: | uc003vho.2 | OMIM ID: | 606085 |
Pubmed: | PMID10950921 | ||
CCDS IDs: | CCDSCCDS5763.1 CCDS CCDS5764.1 |
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011].
Function: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. May act as a tumor suppressor. Inhibits tumor cell growth.
Products for TES gene
Catalog | Product Name | Application | Company |
GFS:E03915 | testis derived transcript (3 LIM domains); ELISA kit | ELISA | n/a |
GFS:A03915 | testis derived transcript (3 LIM domains); Anti | ANTIBODIES | n/a |
GFS:P03915 | testis derived transcript (3 LIM domains); Protien | Protien | n/a |