Symbol: Name: ID: |
TESK2 testis-specific kinase 2 GFS:1551 |
Gene name: | TESK2 |
Chromosome: | 1p32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385204 | Rat Genome Database ID: | RGD:619984 |
HGNC ID: | HGNC:11732 | RefSeq IDs: | NM_007170 |
Entrez Gene ID: | 10420 | Ensembl Gene ID: | ENSG00000070759 |
VEGA IDs: | OTTHUMG00000007680 | UniProt ID: | Q96S53 |
UCSC ID: | uc001cns.1 | OMIM ID: | 604746 |
Pubmed: | PMID10512679 | ||
CCDS IDs: | CCDSCCDS41323.1 |
Dual specificity testis-specific protein kinase 2 is an enzyme that in humans is encoded by the TESK2 gene. This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. [provided by RefSeq].
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Products for TESK2 gene
Catalog | Product Name | Application | Company |
GFS:E01551 | testis-specific kinase 2; ELISA kit | ELISA | n/a |
GFS:A01551 | testis-specific kinase 2; Anti | ANTIBODIES | n/a |
GFS:P01551 | testis-specific kinase 2; Protien | Protien | n/a |